The Chief Investigators will combine their skills to develop new approaches and new knowledge on key nuclear receptor signalling networks in breast cancer that will have important translational applications to clinical care. Furthermore, the Chief Investigators bring with them over 20 Associate Investigators with invaluable scientific and clinical expertise.
The Management team comprises the project Chief Investigators, and Dr Elizabeth Kuczek, the Project Manager, who will monitor and manage the project’s milestones and achievements.
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NRBC Biographies
Professor Christine Clarke, Principal Investigator, Westmead Institute for Cancer Research, Westmead Millenium Institute.
Internationally recognised for her expertise in progesterone receptor mechanisms of action and high-throughput analysis methods on human tissues. Expertise in novel hormone-responsive models of normal human breast. Lead role in national breast cancer tissue bank. Experience in research policy and governance.
Professor Wayne Tilley, Chief Investigator, Dame Roma Mitchell Cancer Research Laboratories, Hanson Institute.
Internationally recognized for his expertise in androgen action in hormone-dependent cancer, expertise in animal models of cancer and explant models of normal breast.
Professor Peter Leedman, Chief Investigator, Western Australian Institute for Medical Research.
Clinical endocrinologist with detailed understanding of hormone action at the clinical level, expertise in co-regulator function in NR activity, microRNAs and in vitro models of breast cancer.
Professor George Muscat, Chief Investigator, Institute for Molecular Bioscience.
Expert in orphan NR function in the context of metabolism which is critical for breast cancer development.
Professor Peter Fuller – Chief Investigator, Prince Henry’s Institute of Medical Research.
Clinical endocrinologist/physician scientist with expertise in the study of the mechanisms of action of non-gonadal sex-steroids which are vital in post- reproductive tract. Extensive experience in research governance.
Professor John Funder – Chief Investigator, Prince Henry’s Institute of Medical Research.
Acknowledged international leader in mineralocorticoid biology, with recognised expertise in integrative endocrine biology, cancer endocrinology and governance. Professor Funder chairs the International Advisory Group.
Professor Evan Simpson – Chief Investigator, Prince Henry’s Institute of Medical Research.
Internationally recognized for his contributions and leadership of research into steroidogenic enzymes in breast cancer, particularly aromatase.
Professor Nadia Rosenthal, Chief Investigator, Australian Regenerative Medicine Institute (Monash).
International leadership experience (Head of EMBL Mouse Biology) and expertise in mouse biology and genetic manipulation, specializing in mouse models of human disease.
Professor Mark Ragan, Chief Investigator, Institute for Molecular Bioscience, ARC Centre for Bioinformatics and Queensland Facility for Advanced Bioinformatics (QFAB).
Expertise in computational biology, large dataset management. high performance computing and knowledge integration in molecular bioscience.
